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The researchers also found that older microdosers showed larger improvement=
s in the psychomotor test, but not cognitive function, than non-microdosers=
. This effect was largely due to older participants over the age of 55 year=
s using a combination of psilocybin, lion=E2=80=99s mane, and niacin.https:=
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In recent years, there has been a resurgence of scientific and popular inte=
rest in the potential use of psychedelic drugs for the treatment of depress=
ion, anxiety, and post-traumatic stress. For instance, psilocybin, the acti=
ve ingredient in magic mushrooms, has shown a tusted Source promise in the =
treatment of individuals with depression, anxiety, and substance use disord=
ers.

Naturally occurring psychedelic substances such as psilocybin extract from =
magic mushrooms and mescaline have been used for their beneficial health ef=
fects for thousands of years.

The classification of psychedelic substances such as psilocybin and LSD as =
drugs of abuse without any medical use has, however, hindered research on t=
he therapeutic effects of these substances.https://buymushroomschocolatebar=
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These studies have generally used regular doses of psilocybin that produce =
euphoric and hallucinogenic effects. However, the use of regular doses of p=
silocybin can also produce unpleasant and terrifying experiences, also refe=
rred to as =E2=80=9Cbad trips=E2=80=9D
The researchers found that microdosers showed greater improvements in mood =
and larger reductions in symptoms of depression, anxiety, and stress over t=
he study period than non-microdosers.

These positive effects of microdosing were observed in all participants, re=
gardless of whether they used psilocybin alone or a combination of either p=
silocybin with lion=E2=80=99s mane, or psilocybin, lion=E2=80=99s mane, and=
 niacin.

Moreover, microdosing psilocybin resulted in similar levels of improvements=
 in mental health and mood across age groups, genders, and among individual=
s who did or did not have mental health concerns.

The only exception was female microdosers who showed larger reductions in d=
epressive symptoms than males.
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In sum, the results of this study add to the current evidence on the benefi=
cial effects of microdosing psilocybin on mental health and mood, including=
 among individuals with mental health concerns.

Microdosing benefits: More research needed
Although the study had a large sample size, the number of individuals in va=
rious subgroups according to age, gender, and substances used for microdosi=
ng was relatively small. Thus, these findings need to be replicated with la=
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Dr. Bal=C3=A1zs Szigeti, a postdoctoral researcher at Imperial College Lond=
on, also noted that the present study used a control group but placebo effe=
cts in the microdosing group cannot be ruled out.

Dr. Szigeti explained:
=E2=80=9CThis study used a natural history control condition, meaning that =
the control group did not have any treatment. This is a weak control condit=
ion, although certainly better than not having any control group as in pure=
ly observational studies.=E2=80=9D https://www.google.com/search?q=3DDr.+Sz=
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=E2=80=9CRelative to this weak control, microdosers showed some improvement=
s, mostly with moderate effect sizes. This means that on most scales the ma=
gnitude of the improvements was only modest. Therefore, this study helps to=
 establish that in uncontrolled / weakly controlled studies microdosing sho=
ws some benefits,=E2=80=9D he continued.

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