Corona Update 24, Mathematical proof self-tests are only 3% correct, 97% false positives !

skybuck2000 <[email protected]> Thu, 17 Feb 2022 11:40:16 -0800 (PST)
Newsgroups alt.comp.lang.borland-delphi
Message-ID <[email protected]>
Corona Update 24, Mathematical proof self-tests are only 3% correct, 97% false positives !

3% of the corona/covid 19 self-tests are correct, 97% are false positives !

The mathematical proof has been delivered (using Bayes' theorem):

Roche's corona self-test has a sensitivity of 96.52% and a specificity of 99.68%.

If "C19" stands for the presence of the disease COVID-19 ("corona") and 
+ and − respectively for a positive and negative result of the test, this means: 

sensitivity: P( + | C19 ): 0.9652

specificity: P( - | not C19): 0.9968

That seems very high. But if the prevalence is only 1 in 10,000, i.e 

prevalence: P( C19 ): 0.0001

This implies:

P( + ) = P( + | C19 ) P( C19 ) + P( + | not C19 ) P ( not C19 ) =

       = 0.9652 x 0.0001 + 0.0032 x 0.9999 = 0.0033
       
and
 
P( C19 | + ) = ( P( + | C19 ) P( C19 ) ) / P( + ) =

             = ( 0.9652 x 0.0001 ) / 0.0033 = 0.03
             

If 10,000 people are tested with this test, including probably 1 infected person, 
then the infected person will almost certainly get a positive result. 
But of the 9,999 uninfected people, 32 will get a false positive result. 
The 9967 people with a negative result are almost certain that they are not infected. 
But of the 33 with a positive result, only 1 is infected, 
only it is unknown who that is. 
So the chance that an individual is actually infected after a positive result 
is only slightly more than 3% in this scenario. 
This self-test is therefore of little use to determine whether you are infected with corona, 
unless the prevalence is around 1% or higher. 

(This information has been known and published since 20 june 2021 !)

Bye,
  Skybuck ! =D