Question about deployment of math computing

Hi

We do math programming (so called machine learning today) in webserver.
The response would be slow, generally it will take 100ms~500ms to finish 
a request.
For this use case, shall we deploy the code within preforked modperl ,or 
event-driven server like dancer/starman?
(we don't use DB like mysql or other slow IO storage server, all 
arguments were passed to webserver by HTTP POST from client).

Thank you.