Integrating a List-Serv into a CMS

Another 'how-to' question...

We've been building our own CMS using ASP.net

We'd now like to add some list-serv capabilities. It's serve two purposes:

1) Traditional list-servs (like this one)
2) a 'this page has been updated' list, where when a page is updated, we
could trigger a message to a specific list 'watching' that page.

I've been looking for 'asp.net based list-servs' but now think that perhaps
there need not be any direct connection between the two products. As long as
the list-serv handles email-based sub and un-subbing, we could probably
programtically send those emails ourselves from our application.

Any thoughts on that? Has anyone integrated a list-serv product with their
CMS, or was it just a write-your-own endeavor?

Finally, has anyone worked with a .net or IIS-centric list-serv that they'd
recommend?

-Darrel