Python and native gdb

Please could anyone advise, is it possible to build a Python enabled
Native GDB similar to the Cross GDB option that exists in
crosstool-ng?

I've made a small change to 300-gdb.sh to add --with-python=python2
for the native GDB build and I'm testing just now, so I guess I'll
find out later today. But I'm thinking it's less trivial than that and
there might be some extra work to be done. Am I right to be sceptical?

Thanks.