Integration problem
"Bastian Hirn-Derksen" <[email protected]> Tue, 13 Apr 2021 16:19:43 +0200
| Newsgroups | gmane.comp.gnu.mcsim |
|---|---|
| Message-ID | <[email protected]> |
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Dear all,=20
=20
I hope someone of you can help me with a problem in GNU McSim I obtain, =
when
I wont to calibrate my model via MCMC. When I start MCMC calibration Im
getting the following error message :
Doing 10000 Metropolis within Gibbs simulations
lsodes-- at start of problem, too much accuracy =20
requested for precision of machine.. see tolsf (=3Dr1)=20
in above message, r1=3D 1.#QNAN00000000
Warning: DoOneExperiment failed
=20
Im aware that there must be an issue with the ode solver and the =
integration
of the data, but Internet research did not provide any solution. I also
tried to set the atol and rtol value to zero for having absolute error
tolerance but this also did not work and occured in this error message:=20
Doing 10000 Metropolis within Gibbs simulations
lsodes-- at start of problem, too much accuracy =20
requested for precision of machine.. see tolsf (=3Dr1)=20
in above message, r1=3D 1.#QNAN00000000
Warning: DoOneExperiment failed
=20
I hope you can help me with this problem. Calibration of the model is
essential for my work and therefore I have to find a solution of the
problem.=20
=20
With kind regards,=20
--
Bastian Hirn-Derksen=20
Apotheker=20
Westf=E4lische Wilhelms-Universit=E4t M=FCnster Institut f=FCr =
Pharmazeutische und
Medizinische Chemie
- Klinische Pharmazie -
Raum A 120.202
Corrensstra=DFe 48
48149 M=FCnster, Germany
Phone: +49 251 83 33364
Fax.: +49 251 83 32144
E-mail: [email protected] <mailto:[email protected]>=20
=20
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link=3D"#0563C1" vlink=3D"#954F72"><div class=3DWordSection1><p =
class=3DMsoNormal>Dear all, <o:p></o:p></p><p =
class=3DMsoNormal><o:p> </o:p></p><p class=3DMsoNormal>I hope =
someone of you can help me with a problem in GNU McSim I obtain, when I =
wont to calibrate my model via MCMC. When I start MCMC calibration Im =
getting the following error message :<o:p></o:p></p><p =
class=3DMsoNormal>Doing 10000 Metropolis within Gibbs =
simulations<o:p></o:p></p><p class=3DMsoNormal>lsodes-- at start of =
problem, too much accuracy=A0 =A0<o:p></o:p></p><p =
class=3DMsoNormal>=A0=A0=A0=A0=A0=A0=A0=A0=A0requested for precision of =
machine..=A0 see tolsf (=3Dr1) <o:p></o:p></p><p class=3DMsoNormal>=A0in =
above message, r1=3D=A0=A0=A0=A0=A0 1.#QNAN00000000<o:p></o:p></p><p =
class=3DMsoNormal>Warning: DoOneExperiment failed<o:p></o:p></p><p =
class=3DMsoNormal><o:p> </o:p></p><p class=3DMsoNormal>Im aware =
that there must be an issue with the ode solver and the integration of =
the data, but Internet research did not provide any solution. I also =
tried to set the atol and rtol value to zero for having absolute error =
tolerance but this also did not work and occured in this error message: =
<o:p></o:p></p><p class=3DMsoNormal>Doing 10000 Metropolis within Gibbs =
simulations<o:p></o:p></p><p class=3DMsoNormal>lsodes-- at start of =
problem, too much accuracy=A0=A0 <o:p></o:p></p><p =
class=3DMsoNormal>=A0=A0=A0=A0=A0=A0=A0=A0=A0requested for precision of =
machine..=A0 see tolsf (=3Dr1) <o:p></o:p></p><p class=3DMsoNormal>=A0in =
above message, r1=3D=A0=A0=A0=A0=A0 1.#QNAN00000000<o:p></o:p></p><p =
class=3DMsoNormal>Warning: DoOneExperiment failed<o:p></o:p></p><p =
class=3DMsoNormal><o:p> </o:p></p><p class=3DMsoNormal>I hope you =
can help me with this problem. Calibration of the model is essential for =
my work and therefore I have to find a solution of the problem. =
<o:p></o:p></p><p class=3DMsoNormal><o:p> </o:p></p><p =
class=3DMsoNormal>With kind regards, <o:p></o:p></p><p =
class=3DMsoNormal>--<o:p></o:p></p><p class=3DMsoNormal>Bastian =
Hirn-Derksen <o:p></o:p></p><p class=3DMsoNormal>Apotheker =
<o:p></o:p></p><p class=3DMsoNormal>Westf=E4lische =
Wilhelms-Universit=E4t M=FCnster Institut f=FCr Pharmazeutische und =
Medizinische Chemie<o:p></o:p></p><p class=3DMsoNormal>- Klinische =
Pharmazie -<o:p></o:p></p><p class=3DMsoNormal>Raum A =
120.202<o:p></o:p></p><p class=3DMsoNormal>Corrensstra=DFe =
48<o:p></o:p></p><p class=3DMsoNormal>48149 M=FCnster, =
Germany<o:p></o:p></p><p class=3DMsoNormal>Phone: +49 251 83 =
33364<o:p></o:p></p><p class=3DMsoNormal>Fax.: +49 251 83 =
32144<o:p></o:p></p><p class=3DMsoNormal>E-mail: <u><span =
style=3D'color:#0563C1'><a =
href=3D"mailto:[email protected]">[email protected]</a></sp=
an></u><o:p></o:p></p><p =
class=3DMsoNormal><o:p> </o:p></p></div></body></html>
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