Proportional error model

"Kondrashina, Anna" <[email protected]> Thu, 7 Dec 2023 11:07:54 +0000
Newsgroups gmane.comp.gnu.mcsim
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Dear MCSim developers,

My name is Anna, for now I am trying to make my own pharmacokinetic using M=
CSim. I want to make my model with the proportional residual error model. D=
o you know how to do it?

Best solution I have found recently is making my own distribution function =
(in mh.c file), that multiplies the variance by the observation before call=
ing the lnDFNormal function. All parameters estimated by the model with my =
likelihood function were normal, except the residual error. It was too big =
to be true.

I am still looking for the ways to introduce the proportional error into my=
 model and will be very glad, if you can help me.

Best regards,
Anna Kondrashina

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<p class=3D"MsoNormal"><span lang=3D"EN-US">Dear MCSim developers, <o:p></o=
:p></span></p>
<p class=3D"MsoNormal"><span lang=3D"EN-US"><o:p>&nbsp;</o:p></span></p>
<p class=3D"MsoNormal"><span lang=3D"EN-US">My name is Anna, for now I am t=
rying to make my own pharmacokinetic using MCSim. I want to make my model w=
ith the proportional residual error model. Do you know how to do it?
<o:p></o:p></span></p>
<p class=3D"MsoNormal"><span lang=3D"EN-US"><o:p>&nbsp;</o:p></span></p>
<p class=3D"MsoNormal"><span lang=3D"EN-US">Best solution I have found rece=
ntly is making my own distribution function (in mh.c file), that multiplies=
 the variance by the observation before calling the
</span><span lang=3D"EN-US" style=3D"font-size:9.5pt;font-family:&quot;Casc=
adia Mono&quot;;color:black">lnDFNormal
</span><span lang=3D"EN-US" style=3D"color:black">function. All parameters =
estimated by the model with my likelihood function were normal, except the =
residual error. It was too big to be true.
<o:p></o:p></span></p>
<p class=3D"MsoNormal"><span lang=3D"EN-US" style=3D"color:black"><o:p>&nbs=
p;</o:p></span></p>
<p class=3D"MsoNormal"><span lang=3D"EN-US" style=3D"color:black">I am stil=
l looking for the ways to introduce the proportional error into my model an=
d will be very glad, if you can help me.
<o:p></o:p></span></p>
<p class=3D"MsoNormal"><span lang=3D"EN-US" style=3D"color:black"><o:p>&nbs=
p;</o:p></span></p>
<p class=3D"MsoNormal"><span lang=3D"EN-US" style=3D"color:black">Best rega=
rds,<o:p></o:p></span></p>
<p class=3D"MsoNormal"><span lang=3D"EN-US" style=3D"color:black">Anna Kond=
rashina</span><span lang=3D"EN-US"><o:p></o:p></span></p>
</div>
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