Re: DNA assembly

Spencer Bliven <[email protected]>
Newsgroups gmane.comp.java.bio.general
Message-ID <CA+P6arkNzfQf=i1F3pdEhCjYQGFJiXZOSxcT61DCG-FuZo5-zA@mail.gmail.com>
If you just have two contiguous sequences to align, you should just use a
global sequence alignment. See
http://biojava.org/wiki/BioJava:CookBook3:PSAfor how to do this in
BioJava, or it might be easier to just use one of the
online services for this such as http://www.ebi.ac.uk/Tools/psa/.

On the other hand, if you actually want to do genome assembly (ie from many
overlapping reads), then there are much more computationally efficient
methods. BioJava isn't really intended for large-scale genome assembly, so
you'd want to use a sequence assembly
tool<http://en.wikipedia.org/wiki/Sequence_assembly>(eg Velvet).

-Spencer


On Tue, Apr 23, 2013 at 12:38 PM, Khalil El Mazouari <
[email protected]> wrote:

> Hi,
>
> I would like to assemble 2 overlapping DNA sequences. Is there something
> in biojava that may help in this task?
>
> Thanks
>
>
>
>
> -----
>
> Confidentiality Notice: This e-mail and any files transmitted with it are
> private and confidential and are solely for the use of the addressee. It
> may contain material which is legally privileged. If you are not the
> addressee or the person responsible for delivering to the addressee, please
> notify that you have received this e-mail in error and that any use of it
> is strictly prohibited. It would be helpful if you could notify the author
> by replying to it.
>
>
>
>
> _______________________________________________
> Biojava-l mailing list  -  [email protected]
> http://lists.open-bio.org/mailman/listinfo/biojava-l
>
_______________________________________________
Biojava-l mailing list  -  [email protected]
http://lists.open-bio.org/mailman/listinfo/biojava-l
lmpx.com only provides a reader for public news (NNTP) servers. It is not affiliated with the servers or forums shown here and is not responsible for the content of articles, which is written by their respective authors.