[Biopython] codon-optimization method
Alex Crocker <[email protected]> Thu, 20 Jul 2023 12:09:56 -0400
| Newsgroups | gmane.comp.python.bio.general |
|---|---|
| Message-ID | <CAM2fN=QY5xmfERquWtR__wW9wW5wVYKMWcaWpGDSMDmuyk7yog@mail.gmail.com> |
Hello, I have added a method for codon optimization of a given sequence (DNA or protein) using the codon preferences contained in a CodonAdaptationIndex object. I created the method because existing fluorophore sequences were not functional in an organism I work with, and I wanted to quickly generate codon-optimized versions of the fluors for my organism. I included the method in biopython/Bio/SeqUtils/__init__.py, inside the CodonAdaptationIndex class. I also added a couple of lines in biopython/Tests/test_SeqUtils.py to apply the method to a sequence and assert that the calculated CAI after optimizing is equal to 1. I read the guidelines for contributing, but am not entirely clear on what I should do next. Would it be appropriate to go ahead and make a pull request? Thank you! Alex _______________________________________________ Biopython mailing list - [email protected] https://mailman.open-bio.org/mailman/listinfo/biopython