[Biopython] Proposal: Advanced peptide descriptors in Biopython (Issue #5100)
Anoop Johny <[email protected]> Fri, 21 Nov 2025 09:41:25 +0000
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Hi all,
I=92ve opened GitHub issue #5100 proposing a new module, Bio.SeqUtils.Pepti=
deDescriptors, to compute advanced descriptors for amino acid sequences (e.=
g., Kidera, Atchley, FASGAI). These are widely used in QSAR modelling, anti=
cancer peptide screening, and clustering; however, Biopython currently supp=
orts only basic properties, such as molecular weight and pI.
I=92d be happy to prototype this with unit tests and documentation if there=
=92s interest. Would others find this useful, and are there particular desc=
riptor sets you=92d prioritise?
Best,
Anoop (GitHub: flyfir248)
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Hi all,</div>
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<div style=3D"font-family: "Baskerville Old Face"; font-size: 12p=
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I=92ve opened GitHub issue #5100 proposing a new module, Bio.SeqUtils.Pepti=
deDescriptors, to compute advanced descriptors for amino acid sequences (e.=
g., Kidera, Atchley, FASGAI). These are widely used in QSAR modelling, anti=
cancer peptide screening, and clustering;
however, Biopython currently supports only basic properties, such as =
molecular weight and pI.</div>
<div style=3D"font-family: "Baskerville Old Face"; font-size: 12p=
t; color: rgb(0, 0, 0);" class=3D"elementToProof">
<br>
</div>
<div style=3D"font-family: "Baskerville Old Face"; font-size: 12p=
t; color: rgb(0, 0, 0);" class=3D"elementToProof">
I=92d be happy to prototype this with unit tests and documentation if =
there=92s interest. Would others find this useful, and are there particular=
descriptor sets you=92d prioritise?</div>
<div style=3D"font-family: "Baskerville Old Face"; font-size: 12p=
t; color: rgb(0, 0, 0);" class=3D"elementToProof">
<br>
</div>
<div style=3D"font-family: "Baskerville Old Face"; font-size: 12p=
t; color: rgb(0, 0, 0);" class=3D"elementToProof">
Best,</div>
<pre class=3D"elementToProof"><div style=3D"font-family: "Baskerville =
Old Face"; font-size: 12pt; color: rgb(0, 0, 0);" class=3D"elementToPr=
oof">Anoop (GitHub: flyfir248)</div></pre>
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