Re: Optimization methods for fitting ODEs

David Hagen <[email protected]> Wed, 11 Mar 2020 10:32:02 -0400
Newsgroups gmane.comp.python.scientific.user
Message-ID <CALO6Ft5h7m=j+SGKUmWD-FoayFR+V3up6E+0VXgUem+CSpi46A@mail.gmail.com>
> I'm not sure I fully understand what you mean by using the gradient.

By analytic gradient, I mean as opposed to a finite difference gradient.
You are correct that I still have to numerically integrate the forward
sensitivities and then propagate the sensitivities via chain rule through
the the objective function.

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