Manipulate PDFs with Malware

Hello everybody,

Let me just explain to you a scenario before I ask my question about
it. You are starting to download a PDF file including a barcode which
is used to identify some payment information like the ammount of money
you have to pay and the receiver, maybe identified by another sequence
which is included.

Would it be possible to manipulate this barcode easily before or
during the opening process of the PDF in order to change the payment
information in a way that the attacker's information is encoded there?

Have you any experience with malware like this?

Best regards,
André

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