New Virus/Worm

Since about 5pm last night, we've been hit hard, so far about 60 computers,
mostly running Windows 2000 got infected.

All infected computers show a backdoor on a random TCP port such as:

xxx.xx.xxx.xxx   5794/tcp  dhcp-xxx-xxx.xxxxxxxxx.xxx
   220 Reptile welcomes you....

Has anyone seen or expierenced similar?

We don't know what processes are running on the PC's until tomorrow when we
can get to them.

Any and all info is greatly appreciated.

Thanks,
-jack