create: Resource temporarily unavailable

I'm seeing erors similar to this on multiple servers:

   error: Could not open database txn /var/cfengine/state/cf_lock.lmdb: 
Invalid argument
   error: Unable to create 
'last.temp_cf_bundle__var_cfengine_templates_main_cf_template.insert_lines.insert_type.-fulla01.insertline_command_directory____usr_sbin__etc_postfix_main_cf_36_2285_MD5=9fdf5ab7b5f56b0e07860f49e4f7c6a4'. 
(create: Resource temporarily unavailable)

What resource is it complaining about?  I radically increased nfiles but it 
had no affect.

root@fulla01-oci [outputs]# ulimit -a
core file size          (blocks, -c) 0
data seg size           (kbytes, -d) unlimited
scheduling priority             (-e) 0
file size               (blocks, -f) unlimited
pending signals                 (-i) 240838
max locked memory       (kbytes, -l) 64
max memory size         (kbytes, -m) unlimited
open files                      (-n) 221184
pipe size            (512 bytes, -p) 8
POSIX message queues     (bytes, -q) 819200
real-time priority              (-r) 0
stack size              (kbytes, -s) 8192
cpu time               (seconds, -t) unlimited
max user processes              (-u) 240838
virtual memory          (kbytes, -v) unlimited
file locks                      (-x) unlimited

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