Measuring performance and finding bottleneck

Hi,

Our portal has a big issue with performance
I want to ask you to give me advice about tools which the best for
measuring performance and finding bottleneck.
Here the list of tools that I found.

   1. Standard Zope profiler
   2. collective.stats https://pypi.python.org/pypi/collective.stats
   3. Zope Profiler https://pypi.python.org/pypi/Products.ZopeProfiler
   4. z3c.profiler https://pypi.python.org/pypi/z3c.profiler
   5. Products.MemoryProfiler
   https://pypi.python.org/pypi/Products.MemoryProfiler
   6. Products.PTProfiler https://pypi.python.org/pypi/Products.PTProfiler
   7. collective.profiler https://pypi.python.org/pypi/collective.profiler
   8. haufe.requestmonitoring
   https://pypi.python.org/pypi/haufe.requestmonitoring
   9. collective.traceview https://pypi.python.org/pypi/collective.traceview
   10. RunSnakeRun http://www.vrplumber.com/programming/runsnakerun/


Best regards,
Bogdan.

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