Dependency of Debian-Med packages on Apache2 web server

Hi,

As you might remember, I have promoted the use of "x2go" for remote 
bioinformatics desktops running Debian-Med packages. However, it is 
getting increasingly difficult to obtain SSH access (used by "x2go") 
through firewalls and MFA (Multi-Factor Authentication) systems.

I'm now running "noVNC" instead, via a reverse proxy using NGINX, but 
installing "nginx" on a 'clean' install of "med-bio" under Ubuntu-MATE 
22.04 forces the removal of packages that depend on "apache2". I have 
managed to reverse-proxy to "noVNC" from Apache2, but NGINX is the 
recommended web server to reverse-proxy to "noVNC".

I realise that there are ways of running both Apache2 and NGINX on the 
same server, but I would like to know what Debian-Med "med-bio" packages 
*actually* need Apache2 because it requires quite a lot of manual 
configuration to get e.g. NGINX to use Apache2 as a reverse proxy.

I'd welcome any help or advice about NGINX and Apache2 co-existence.

Thanks,

   Tony.