The place of mimeinfo.cache in freedesktop specs

mimeinfo.cache is automatically generated file by update-desktop-database.
Is it part of some spec? When are desktop environments expected to
re-generate mimeinfo.cache?

E.g. I'm writing installation script and it also install .desktop file with
some new MimeType. Should I call update-desktop-database or expect DE to
rebuild it for me?

I also found that xdg-open does not take mimeinfo.cache files into account,
so applications that use xdg-open sometimes fail to properly open programs
associated with the url unless association is in mimeapps.list.

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