Variables in rc file?

Juan Simón <[email protected]> Fri, 29 Apr 2016 10:00:02 +0200

Newsgroups	gmane.network.lftp.user
Message-ID	<CAMQzBqAJV3dpJA_dYt7VvJ2pabMk6ZxJBaA55h7tw5orvkyYLQ@mail.gmail.com>

Is there possible to use variables in rc file (similar to BASH, ZSH, etc.)?
For example, to define the HOME folder.

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