what drives sample outliers in 450k (detectOutlier, lumi)

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Hi there

I am finding some sample outliers in the result from the detectOutlier meth=
od in lumi. I don=92t see anything strange about these samples when I look =
at the mean beta values. I wonder how I can find out what drives these samp=
les to be outliers (what set of probes, etc)? It would be good to know the =
reason for these, to determine whether they need to be re-included in a sep=
arate experiment. They do not seem to be outliers in the gender tests ..=20

I would appreciate your thoughts on this.=20

Many thanks
Victoria


--
Victoria Svinti
Colon Cancer Genetics Group
MRC Human Genetics Unit, IGMM
University of Edinburgh, Western General Hospital,
Crewe Road, Edinburgh, EH4 2XU





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