Any simple clustering program for Hierarchical Single Linkage available?

"Shalini Sridhar" <[email protected]> Sun, 18 Jun 2006 06:52:46 +0000
Newsgroups gmane.science.biology.informatics.devel
Message-ID <[email protected]>
Hello All,

I need a simple , freely downloadable , Clustering program , that will cluster a large number of records (>10,000) using Hierarchical Clustering Methods, and using Single Linkage Clustering Technique.

I would like to cluster a large number of proteins based on a similarity score that will be used as input and to output a tree in the form of a text file.

This program needs to be run from command line, prefereably a C executable from a UNIX machine. The input would be a text file of a distance matrix and the output will also be a text file of clusters or dendrograms.

I came across OC - Geoffery Barton - University of Dundee, that fits my required description, however the output is just a PS file, and thus cannot be manipulated further.

I also came across Eisen Lab's - CLuster3.0 , however, this is more complicated and used for mostly microarray data, since the input and output file fits the requirement for microarray sets.

Could someone please suggest me a simple program that would fit my description required? Would really appreciate it.

Thank you.

Shalini Sridhar

MRes.Bioinformatics and Computational Biology, Univ of Leeds,Leeds.

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