Re: Looking for repeat motifs - ideas?
"Michael Nuhn" <[email protected]> Thu, 28 Feb 2008 12:20:31 +0100
| Newsgroups | gmane.science.biology.informatics.devel |
|---|---|
| Message-ID | <001001c879fb$ee05f860$80baf683@nbc1> |
Hi, Jeff! > What threshold would you use for gaps and mismatches? I would look for about 1 mismatch in the repeat and a gap of about 4-6bp. But that can vary a bit. The bigger picture for me is to not only look for the one case but to make a tool that can do similar searches and is easy to use. I have started here: http://nbc11.biologie.uni-kl.de/motifsearch2/index.pl (Link may change in the future) >If you can have any >number of mismatches within the motif and >any size gap, it becomes more of >problem in pattern recognition. The whole thing is geared more to find candidates for sequences that regulate transcription. No pathological cases. ;-) Cheers, Michael.