fractional freezing

At 09:59 PM 3/1/2004 +0100, John H. Dom wrote:
>Does anyone have hands-on experience with the formulations in this USP?:
>
>6,419,771

 From the introduction, discussing HTP concentration methods:

"Fractional crystallization is also a difficult separation
technique due to water occlusion in hydrogen peroxide crystals."

IOW, fractional freezing tends to trap unfrozen water in the
matrix of frozen peroxide crystals.  Presumably this reduces
yield-per-pass, but not the ultimate quality of the product.
Does the proposed fractional freezing system have a proposed
method to deal with this difficulty?

Cheers!
--Stu