K D E, at this time

I am an Orca user familiar with gnome and mate.
I am no programmer, just an end user.
For a linux user, using the Orca screen-reading program and keyboard =
shortcuts, and not the mouse, would there be any advantage of using one =
desktop over another?
At this time, which desktops are usable for Orca users?
Also, how usable is k d e at this stage?=