Re: Re: bug free cowboy camping

Thanks for the responses with papers.

Something to think about when balancing risks.

The more credible information, the better.


Ralph  (enjoying a good reasonable discussion)


On Fri, Apr 12, 2013 at 10:33 AM, greatyoga <greatyoga-/[email protected]> wrote:

> Occupational Use of 2,4-D, Permethrin Triple the Risk of Parkinson's
> Disease
>
> (Beyond Pesticides, September 16, 2009) A new study published in the
> September issue of Archives of Neurology reports that the risk of
> Parkinsonism doubled with increased occupational exposure to pesticides,
> including eight agents associated with experimental Parkinsonism. These
> data add to the growing number of studies that lend credence to a causative
> role of certain pesticides in neurological disorders.
>
> The study, "Occupation and Risk of Parkinsonism: A Multicenter
> Case-Control Study," set out to investigate occupations, specific job
> tasks, or exposures and risk of parkinsonism in collaboration with eight
> movement disorders centers in North America including, the Parkinson's
> Institute, CA, Department of Neurology, Baylor College of Medicine and
> Department of Neurology, Beth Israel Medical Center, New York. The
> investigation focused on five occupations previously suggested as posing an
> increased risk of Parkinsonism: agriculture, education, healthcare,
> welding, and mining. This examination of toxicant exposures included
> solvents and pesticides putatively associated with Parkinsonism. 519 people
> with Parkinson's disease and 511 similar people who did not have
> Parkinson's were studied.
>
> Overall, the study finds that those whose jobs involve using pesticides
> are 80 percent more likely to develop the condition. The data reveals that
> any exposure to the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) almost
> triples the risk of Parkinsonism compared with individuals who report no
> exposure to the agent. The herbicide paraquat and the insecticide
> permethrin are also associated with a more than three-fold increased risk
> of Parkinson's disease.
>
> "Occupational pesticide exposure emerges as the most consistent etiologic
> association with Parkinsonism," Caroline M. Tanner, MD, PhD, of the
> Parkinson's Institute in Sunnyvale, CA. Those who worked in agriculture,
> education, health care, or welding but who had not been exposed to
> pesticides through their work were not likely to develop the disease. The
> researchers note that while they did not look at pesticide exposures such
> as hobby gardening or residential exposure, "because these exposures may
> affect many more subjects, future attention is warranted."
>
> Previous studies have linked pesticide exposure to the onset of
> Parkinson's disease (PD), including several published this year alone. A
> similar study conducted by French researchers found that farmworkers who
> used insecticides had over a two-fold increase in the risk of PD. Another
> recent publication found that rural residents who drank contaminated well
> water had an increased (up to 90 percent) risk of developing PD. Exposure
> to the pesticides, paraquat and maneb, within 500 meters of an individual's
> home, increased the risk of developing Parkinson's by 75 percent, according
> to a University of California, Berkeley study. The Institute of Medicine
> (IOM) found suggestive but limited evidence that exposure to Agent Orange
> and other herbicides used during the Vietnam War is associated with an
> increased chance of developing ischemic heart disease and Parkinson's
> disease in Vietnam veterans.
>
> Parkinson's Disease is the second most common neurodegenerative disease
> affecting more than one million people in the U.S. Parkinson's disease
> occurs when nerve cells in the substantia nigra region of the brain are
> damaged or destroyed and can no longer produce dopamine, a nerve-signaling
> molecule that helps control muscle movement. All three pesticides in this
> study; 2,4-D, paraquat and permethrin, have effects on dopaminergic
> neurons. All three pesticides are currently registered for use in the U.S.
> 2,4-D is a herbicide most commonly found in many popular lawn care
> products, while permethrin is an insecticide (synthetic pyrethroid) found
> in many mosquito products and residential bug sprays. Both chemicals are
> already linked to cancer, endocrine disruption and other reproductive and
> developmental effects. Paraquat is a restricted-use pesticide (RUP) used
> primarily in agriculture.
>
> For more on Parkinson's disease, please read "Pesticides Trigger
> Parkinson's Disease," a review of published toxicological and
> epidemiological studies that link exposure to pesticides, as well as
> gene-pesticide interactions, to Parkinson's disease and published in
> Pesticides and You (spring 2008).
>
> Source: Reuters
>
> Feline permethrin toxicity: retrospective study of 42 cases.
> Boland LA, Angles JM.
> Source
>
> Department of Clinical Veterinary Science, Division of Companion Animals,
> University of Bristol, Langford, Bristol BS40 5DU, United Kingdom.
> Abstract
>
> Forty-two cases of feline permethrin toxicity treated at a referral
> hospital in Sydney, Australia were retrospectively reviewed. In most cases
> canine permethrin spot-on (PSO) flea products had been directly applied to
> affected cats. Most presented during summer and there was an increase in
> cases during the 2007/2008 period. Clinical signs included; tremors/muscle
> fasciculations (86%), twitches (41%), hyperaesthesia (41%), seizures (33%),
> pyrexia (29%), ptyalism (24%), ataxia (24%), mydriasis (19%) and temporary
> blindness (12%). Treatment involved decontamination, anticonvulsants and
> supportive care. Methocarbamol was not used. Complications occurred in 33%
> of cats and included: hypothermia (29%), electrolyte abnormalities (26%),
> aspiration pneumonia (12%), hypoproteinaemia (12%), anaemia (5%), apnoea
> (7%), respiratory arrest (5%), cardiorespiratory arrest (2%), pleural
> effusion (2%), urinary tract infection (2%) and corneal ulceration (2%).
> One cat was euthanased. Feline permethrin toxicity may result in severe
> clinical signs requiring intensive treatment. Despite prominent label
> warnings, cases of feline permethrin toxicity continue to occur in
> Australia and may be fatal.
>
> Copyright 2009 ESFM and AAFP. Published by Elsevier Ltd. All rights
> reserved.
>
> --- In [email protected], Ralph Oborn <Ralph.oborn@...>
> wrote:
> >
> > Please share this evidence.
> >
> > Ralph
> >
> >
> > On Thu, Apr 11, 2013 at 11:09 AM, greatyoga <greatyoga@...> wrote:
> >
> > > Jerry,
> > >
> > > I would not go so far as to say no effect.  It can be fatal for cats.
> > >  There is also evidence it can be a prelude to Parkinson's in humans.
> > >
> > > GB
> > >
> > > --- In [email protected], "Jerry Goller" <jerrygoller@>
> > > wrote:
> > > >
> > > >
> > > >
> > > > I assume the clothes have been allowed to dry completely before
> wearing
> > > them. Since permethrin has no effect on mammals, what happens if the
> > > “excess† isn’t washed off?
> > > >
> > > >
> > > >
> > > > Jerry
> > >
> > >
> > >
> > >
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